When Should Autoantibody Screening be Carried out?
A test for autoantibodies is recommended in cases of unclear organ-specific or systemic processes. However, targeted serological screening is only sensible if clinical symptoms suggest disease. In such cases serological tests should be among the first diagnostic measures, because they not only allow for a precise and technically simple definition of an unclear clinical picture, but also for the early introduction of immunosuppressive or anti-inflammatory treatments. Sometimes detection of autoantibodies can be a useful indicator of successful treatment, making it possible to follow the progression of the disease.