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Autoimmunity - an Introduction

Autoimmune Diseases I

In multiple sclerosis, nerve cells and their sheathing are massively damaged and then destroyed by attacking self-destructive T cells. This results in neurological deficits like impaired vision, paraesthesia, spastic tonicity and paralysis.

A healthy nerve cell with intact myelin sheath
© Orgentec Diagnostika
Auto reactive macrophages attack the myelin sheath of a nerve cell in multiple sclerosis
© Orgentec Diagnostika

In type 1 diabetes, the body forms antibodies against the insulin-producing islet cells in the pancreas, and in vasculitis; an autoimmune process is responsible for a life-threatening inflammation of the blood vessel walls.

Symptoms of Wegener's disease, an autoimmune inflammation of small blood vessels
© Orgentec Diagnostika
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