Reduction of Nitro Compounds to Amines
Reduction of Nitro Compounds to Amines: Introduction
Nitro groups can be easily reduced to amino groups with metals, such as zinc, tin and iron, in acidic solution. Additional methodologies involve catalytic hydrogenation and the use of reducing agents, such as hydrazine and titanium trichloride.
The reaction mechanism of the reduction of nitro groups with metals in acidic solution is analogous to the reduction of carbonyl groups under similar conditions.
- Industrial preparation of aniline from nitrobenzene.