zum Directory-modus

Reduction of Nitriles to Amines

Reduction of Nitriles to Amines: Reduction with Lithium Aluminum Hydride

Transfer of a hydride ion from lithium aluminum hydride to the carbon atom of the nitrile generates an imine intermediate, which is in equilibrium with the corresponding imino alanate.


The imino alanate converts to the amino alanate after adddition of an additional hydride ion.


Hydrolysis yields the primary amine.

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