Comparison of Various Hydrogenation Methods
Overview of Reductions of Organic Compounds
- Tab.1
- Overview of the most important reductions, reducing agents and selectivities
| Educt | Product | H2 / cat | NaBH4 | LiAlH4 | B2H6 | Li/Na |
|---|---|---|---|---|---|---|
| + | - | - | + | O | ||
| + * | - | - | O | + | ||
| - | - | - | - | + | ||
| + | - | - | - | - | ||
| + | - | + | - | + | ||
| + | - | - | - | + | ||
| + | - | - | - | + | ||
| + | - | + | + | + | ||
| +** | - | - | - | + | ||
| + | - | - | - | + | ||
| O | O | O | O | O | ||
| O | + | + | + | + | ||
| - | - | + | + | - | ||
| O | - | + | O | O | ||
| +**** | O | O | - | - | ||
| - | + | O | - | - | ||
| - | - | + | + | - | ||
| + | - | + | + | + |
- Tab.2
- Symbols
| + | synthetically applicable |
|---|---|
| O | limited application |
| - | not reactive |
| * | Lindlar catalyst |
| ** | Raney nickel (works also without H2 ) |
| *** | see Wolff-Kishner and Clemmensen reduction |
| **** | Rosenmund reduction (poisoned Pd catalyst) |
