zum Directory-modus

Oxidation of Amines to Nitroso Compounds

Oxidation of Amines to N-Nitrosamines: Laboratory Application

N-Nitrosamides or N-acyl-N-nitrosoalkylamines can be prepared from primary alkyl amides by reaction with nitrosyl cation.

Alkaline cleavage of the N-nitrosamide generates the intermediate diazotic acid which decomposes to diazoalkane.

Synthesis of diazoalkanes
3D model of diazomethane

Diazoalkanes are used in inorganic chemistry as nitrogen transfer agents and as alkylating reagents in organic chemistry.

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