zum Directory-modus

Dihydroxylation of Alkenes

Cis-dihydroxylation of Alkenes: Introduction

Reaction principle

Potassium permanganate or osmium tetroxide add to the less hindered side of the double bond of the alkene forming a cyclic intermediate. Addition of water destroys the ring and liberates the cis 1,2-diol. Initially, potassium permanganate loses one oxygen atom and is transformed into manganese dioxide while osmium tetroxide is reduced to osmic acid.

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