zum Directory-modus

Aromatisation of Six-Membered Rings

Aromatization of Six-Membered Rings: Oxidation with Sulfur or Selenium

Sulfur and selenium are mild oxidizing agents. Temperatures between 220 und 330°C are required for the reaction to take place. The development of either hydrogen sulfide or selenium sulfide during the reaction limits the preparative value of this otherwise simple process.

The reaction was successfully used in the structure determination of terpenes and steroids, because known aromatic systems were formed in the transformation.

Fig.1
Selenium oxidation of steroids

Occasionally, changes in the carbon skeleton and functional groups were observed under the harsh conditions of the reaction.

Page 4 of 6