ChemieOrganische ChemieSubstitution

First, this learning unit describes the mechanistic reasons for the competition of elimination and nucleophilic substitution. Then, the different parameters that influence the SN2/E2 competition are discussed. After working through the learning unit, one should be able to predict, depending on given parameters, the predominant mechanism of a reaction or to choose the parameters of a reaction, so that a mechanism desired actually mainly occurs, respectively.

Author

• Prof. Dr. Gregor Fels
• Dr. Carsten Biele

Translators

• Dr. Carsten Biele

Learning objective

• Fundamentals of the competition of elimination and nucleophilic substitution.
• Parameters that influence the SN2/E2 competition.
• Prediction of the predominant reaction mechanism depending on the different parameters.

Important Keywords in this Learning Unit

elimination, transition state, reaction rate, nucleophile