Course id: 80328
SN/E Competition - SN1/E1 Competition
First, this learning unit describes the mechanistic reasons for the competition of elimination and nucleophilic substitution. Then, the different parameters that influence the SN1/E1 competition are discussed. After working through the learning unit, one should be able to predict, depending on given parameters, the predominant mechanism of a reaction or to choose the parameters of a reaction, so that a mechanism desired actually mainly occurs, respectively.
Learning objectives
- Fundamentals of the competition of elimination and nucleophilic substitution.
- Parameters that influence the SN1/E1 competition.
- Prediction of the predominant reaction mechanism depending on the different parameters.
Categorization
Learning Time: 30 min
Level of Difficulty: high
Requirements
- Reactions and mechanisms of elimination and nucleophilic substitution.
- SN1/SN2 competition.
- E1/E2 competition.
Continuative Learning Units
Keywords
nucleophilic substitution, elimination, beta elimination, competition, transition state, energy, substrate structure, reaction rate, carbenium ion, trigonal planar, basicity, nucleophile, nucleophilicity, base
Authors
Dr. Carsten Biele | Prof. Dr. Gregor Fels
Translators: Dr. Carsten Biele
