ChemieOrganische ChemieAromatenchemie

First, the learning unit describes the mechanism of electrophilic aromatic substitution inclusive of energetics, intermediates, and transition states. Further, it is discussed in which way the inductive and mesomeric effects of first substituents influence the reactivity of substituted aromatic compounds in second substitution.

Author

• Prof. Dr. Gregor Fels
• Dr. Oliver Kamp
• Dr. Carsten Biele

Translators

• Dr. Carsten Biele

Learning objective

• Mechanism of electrophilic aromatic substitution - Ar-SE.
• Course of energy in electrophilic aromatic substitution.
• Inductive and mesomeric effects on the reactivity of substituted aromatic compounds.
• Regioselectivity in second electrophilic aromatic substitution.

Important Keywords in this Learning Unit

inductive effect, mesomerism