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Links und Literatur

Zellkern (Nucleus)


Belandia, B.; Parker, M. G. (2003): Nuclear receptors: a rendezvous for chromatin remodeling factors. In: Cell. 114 (3) , 277-280
Titel des Artikels
Nuclear receptors: a rendezvous for chromatin remodeling factors
Nuclear receptors (NRs) are a large family of ligand-induced transcription factors that include the vitamin D receptor. The recent discovery of WINAC, a novel ATP-dependent chromatin remodeling complex, has shed new light on the molecular mechanisms by which the vitamin D receptor controls gene expression with unexpected clinical implications.
Eichler, E. E.; Sankoff, D. (2003): Structural dynamics of eukaryotic chromosome evolution. In: Science. 301 , 793-797
Fahrenkrog, B.; Aebi, U. (2003): The nuclear pore complex: nucleocytoplasmic transport and beyond. In: Nat. Rev. Mol. Cell Biol.. 4 , 757-766
Fromont-Racine, M.; Senger, B.; Saveanu, C.; Fasiolo, F. (2003): Ribosome assembly in eukaryotes. In: Gene. 313 , 17-42
Titel des Artikels
Ribosome assembly in eukaryotes
Ribosome synthesis is a highly complex and coordinated process that occurs not only in the nucleolus but also in the nucleoplasm and the cytoplasm of eukaryotic cells. Based on the protein composition of several ribosomal subunit precursors recently characterized in yeast, a total of more than 170 factors are predicted to participate in ribosome biogenesis and the list is still growing. So far the majority of ribosomal factors have been implicated in RNA maturation (nucleotide modification and processing). Recent advances gave insight into the process of ribosome export and assembly. Proteomic approaches have provided the first indications for a ribosome assembly pathway in eukaryotes and confirmed the dynamic character of the whole process.
Gurdon, J. B.; Byrne, J. A.; Simonsson, S. (2003): Nuclear reprogramming and stem cell creation. In: Proc. Natl. Acad. Sci. USA. 100 , 11819-11822
Lamond, A. I.; Spector, D. L. (2003): Nuclear speckles: a model for nuclear organelles. In: Nat. Rev. Mol. Cell Biol.. 4 , 605-612
Lamond, A. I.; Sleeman, J. E. (2003): Nuclear substructure and dynamics. In: Curr. Biol.. 13 , R825-R828
Leung, A. K. L.; Lamond, A. I. (2003): The dynamics of the nucleolus. In: Crit. Rev. Eukaryot. Gene Expr.. 13 , 39-54
Levine, M.; Tjian, R. (2003): Transcription regulation and animal diversity. In: Nature. 424 , 147-151
Martin, W. (2003): Gene transfer from organelles to the nucleus: frequent and in big chunks. In: Proc. Natl. Acad. Sci. USA. 100 , 8612-8614
Mattaj, I. W. (2004): Sorting out the nuclear envelope from the endoplasmic reticulum. In: Nat. Rev. Mol. Cell Biol.. 5 , 65-69
Mattout-Drubezki, A.; Gruenbaum, Y. (2003): Dynamic interactions of nuclear lamina proteins with chromatin and transcriptional machinery. In: Cell. Mol. Life Sci.. 60 , 2053-2063
Zlatanova, J.; Leuba, S. H. (2003): Chromatin fibers, one-at-a-time. In: J. Mol. Biol.. 331 , 1-19

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