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Antioxidatives Schutzsystem

Literatur

Literatur

(2005): Oxidants and antioxidant defense systems. Tillmann Grune (Hrsg.). Springer Verlag
Littarru, G. P. (1994): Energie und Schutz - Coenzym Q10: Fakten und Perspektiven in der Biologie und Medizin. Casa Editrice Scientifica Internationale, ISBN: 88-86062-12-5
(1995): Oxidantive Stress and Aging. R. Cutler G. L. Packer J. Bertram A. Mori (Hrsg.). Birkhäuser Verlag, ISBN: 3-7643-50393
(1995): Analysis of Free Radicals in Biological Systems. A. Favier E. J. Cadet B. Kalyanaraman M. Fontecave J. Pierre L. (Hrsg.). Birkhäuser Verlag, ISBN: 3-7643-5137-3
Watzl, B.; Leitzmann, C. (1995): Bioaktive Substanzen in Lebensmitteln. Hippokrates, ISBN: 3-7773-1115-4
Albanes, D.; Malila, N.; Taylor, P. R.; Huttunen, J. K.; Virtamo, J.; Edwards, B. K.; Rautalahti, M.; Hartman, A. M.; Barrett, M. J.; Pietinen, P.; Hartman, T. J.; Sipponen, P.; Lewin, K.; Teerenhovi, L.; Hietanen, P.; Tangrea, J. A.; Virtanen, M.; Heinonen, O. P. (2000 ): Effects of supplemental alpha-tocopherol and beta-carotene on colorectal cancer: results from a controlled trial (Finland). In: Cancer Causes Control.. 3 , 197-205
Crapo, J. D.; Tierney, D. F. (1974): Superoxide dismutase and pulmonary oxygen toxicity. In: Am. J. Physiol.. 226 , 1401-1407
McCord, J. M. (2000): The evolution of free radicals and oxidative stress. In: Am. J. Med.. 108 (8) , 652-659
Titel des Artikels
The evolution of free radicals and oxidative stress
Abstract
The superoxide free radical has come to occupy an amazingly central role in a wide variety of diseases. Our metabolic focus on aerobic energy metabolism in all cell types, coupled with some chemical peculiarities of the oxygen molecule itself, contribute to the phenomenon. Superoxide is not, as we once thought, just a toxic but unavoidable byproduct of oxygen metabolism. Rather it appears to be a carefully regulated metabolite capable of signaling and communicating important information to the cell’s genetic machinery. Redox regulation of gene expression by superoxide and other related oxidants and antioxidants is beginning to unfold as a vital mechanism in health and disease.
Miller, E. R.; Pastor-Barrusio, R.; Dalal, D.; Riemersma, R. A.; Appel, L. J.; Guallar, E. (2005): Meta-Analysis: high-dose Vitamin E supplementation may increase all-cause mortality. In: Ann. Intern. Med.. 142 , 37-46
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