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Subject - Biochemistry, Immunology

Psueodopodia (from greek pseudein "false" and podion "foot") are temporary projections of the plasma of phagocytic cells and amoebae, which serve to move the cell or to absorb particles into the cell. In this process, the cell first forms a bulge in one spot, into which more and more plasma flows to enlarge the pseudopod. This projection can then surround a bacterium, for example, which can then be absorbed into the cell by way of a food vacuole (phagocytosis). The movement of the plasma is effected in part by a network of actin and myosin filaments that pervades the entire cell.

In humans, many cell types are able to move in an amoeboid fashion. These include plasma cells, macrophages, eosinophil granulocytes and mast cells within tissues, but also lymphocytes and monocytes in the blood. The phagocytic activity of the macrophages plays an important role in the immune defence.