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endoplasmic reticulumZoomA-Z

Subject - cell biology

The endoplasmic reticulum (abbreviated ER) is a system of flattened tubes that are essentially an extension of the nuclear membrane. The ER is where folding and post-translational modifications of proteins, as well as the transport of transmembrane proteins and secretory proteins (exocytosis), occurs.

In the rough endoplasmic reticulum (RER), which is covered with ribosomes, proteins destined for uptake into the ER (transmembrane and secretory proteins) are translated. The smooth ER is necessary for the synthesis of various lipids and steroids (hormones), and plays an important role in cell detoxification.

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