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E2 eliminationZoomA-Z

Subject - Organic Chemistry

Description of the mechanism of an elimination reaction. Contrary to E1 eliminations in which the leaving group is eliminated first and a proton is subsequently abstracted in the second step, E2 eliminations are synchronized, i.e. both groups depart simultaneously. An example for this reaction type is the dehydrohalogenation of halogen alkanes.

Mechanism: E2 elimination

As a rule, E2 eliminations proceed stereospecifically in an anti fashion, i.e. the groups to be eliminated occupy an anti periplanar conformation