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E2 eliminationZoomA-Z

Subject - Organic Chemistry

Description of the mechanism of an elimination reaction. Contrary to E1 eliminations in which the leaving group is eliminated first and a proton is subsequently abstracted in the second step, E2 eliminations are synchronized, i.e. both groups depart simultaneously. An example for this reaction type is the dehydrohalogenation of halogen alkanes.

Fig.1
Mechanism: E2 elimination

As a rule, E2 eliminations proceed stereospecifically in an anti fashion, i.e. the groups to be eliminated occupy an anti periplanar conformation