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Subject - Biochemistry

The steroid cholest-5-en-3β-ol (cholesterol) is found in the plasma membranes of eukaryotic cells and presumably regulates the fluidity of the membrane. Additionally, cholesterol is the precursor of the steroid hormones testosterone, progesterone, estradiol, and cortisol. Furthermore, the salts of bile acid (cholates) are derived from cholesterol. The synthesis of cholesterol mainly takes place in the liver but also in the intestines of mammals.

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Structural formulas of cholesterol and cholestane

5,6-Epoxycholesterol (oxycholesterol) is implicated in the development of atherosclerosis. It develops during cellular oxidative stress and inadequate function of the antioxidative protection system.

5α-Cholestane is the basic structure of sterols.

See also: steroid